Mougeot, Romain’s team published research in European Journal of Organic Chemistry in 2022-01-17 | CAS: 100-70-9

European Journal of Organic Chemistry published new progress about Fluorescent dyes. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Quality Control of 100-70-9.

Mougeot, Romain published the artcileConvergent and Practical Synthesis of Fluorescent Triphenylamine Derivatives and Their Localization in Living Cells, Quality Control of 100-70-9, the main research area is pyridine oxazole thiazole preparation fluorescence.

In the search for new fluorescent triphenylamine (TP) derivatives, authors studied the influence of the position and substitution of diverse heterocyclic substituents. A library of 10 fluorescent triphenylamines bearing either oxazoles or thiazoles and pyridiniums, substituted at different positions has been developed. The approach is based on a convergent C-H activation reaction between pyridine-oxazoles or pyridine-thiazoles and di-iodo triphenylamine. Author’s showed that the nature and substitution pattern of the 5-membered- (oxazole, thiazole) or 6-membered heterocycle (pyridine) has a strong influence on their fluorescence properties and on their localization in living cells as they stain either the nucleus or mitochondria.

European Journal of Organic Chemistry published new progress about Fluorescent dyes. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Quality Control of 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts