Mass spectra of substituted N-alkylpyrroles and related compounds was written by Lin, Shaw Tao;Shiue, Gong Yih;Kuo, Yueh Hsiung;Shih, Kae Shyang. And the article was included in Journal of the Chinese Chemical Society (Taipei, Taiwan) in 1994.Synthetic Route of C7H6N2O The following contents are mentioned in the article:
Under EI conditions, substituents on N-alkylpyrroles affect fragmentation of the alkyl groups. The electron-withdrawing character of the cyano group retarded formation of an N-methylene cation, and a labile substituent, i.e., CHO, CH2COOMe, competed with an N-alkyl group to be an initial fragmentation center. MNDO calculation of the heat of formation of possible fragment ions showed that protonated pyridine is the most stable among the isobaric ions. This study involved multiple reactions and reactants, such as 5-Formyl-1-methyl-1H-pyrrole-2-carbonitrile (cas: 81698-03-5Synthetic Route of C7H6N2O).
5-Formyl-1-methyl-1H-pyrrole-2-carbonitrile (cas: 81698-03-5) belongs to nitriles. Trimerization of aromatic nitriles requires harsh reaction conditions, high temperatures, long reaction times, and pressure. In conventional organic reductions, nitrile is reduced by treatment with lithium aluminium hydride to the amine. Reduction to the imine followed by hydrolysis to the aldehyde takes place in the Stephen aldehyde synthesis, which uses stannous chloride in acid.Synthetic Route of C7H6N2O
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts