Synthesis of C1-symmetric chiral tripodal oxazolines through an oxazoline exchange reaction with amino alcohols was written by Kim, Sung-Gon;Seong, Hye Ran;Kim, Jeongryul;Ahn, Kyo Han. And the article was included in Tetrahedron Letters in 2004.Category: nitriles-buliding-blocks The following contents are mentioned in the article:
Various C1-sym. chiral tripodal tris(oxazolines), e.g., I, with two different oxazoline units were synthesized from chiral C3-sym. tris(oxazolines) through an oxazoline exchange reaction with amino alcs. in the presence of zinc chloride. Evaluation of the oxazolines as chiral mol. receptor showed that some of the receptors have chiral discrimination ability. This study involved multiple reactions and reactants, such as 2,2′,2”-(2,4,6-Trimethylbenzene-1,3,5-triyl)triacetonitrile (cas: 16144-65-3Category: nitriles-buliding-blocks).
2,2′,2”-(2,4,6-Trimethylbenzene-1,3,5-triyl)triacetonitrile (cas: 16144-65-3) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. Both routes are green in the sense that they do not generate stoichiometric amounts of salts.Category: nitriles-buliding-blocks
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts