Tripodal (N-alkylated) CMP(O) and malonamide ligands: synthesis, extraction of metal ions, and potentiometric studies was written by Janczewski, Dominik;Reinhoudt, David N.;Verboom, Willem;Malinowska, Elzbieta;Pietrzak, Mariusz;Hill, Clement;Allignol, Cecile. And the article was included in New Journal of Chemistry in 2007.Synthetic Route of C15H15N3 The following contents are mentioned in the article:
Tripodal ligands build on the C-pivot (9b-e, 13b-d, and 17a-d) and trialkylbenzene platforms (10a,b, 11, 12, 14a,b, and 18a,b) bearing (N-alkylated) carbamoylmethylphosphine oxide (CMPO), carbamoylmethylphosphonate (CMP), and malonamide moieties were synthesized. Extraction studies with Am3+ and Eu3+ show that in general there is a pos. influence of the N-alkyl substituents in C-pivot CMP(O) ligands on the D (distribution) coefficients The trialkylbenzene CMPO ligands 10a,b, 11, and 12 have considerably larger D coefficients than the corresponding C-pivot analogs 9a-e, although hardly having any selectivity, while N-alkylation gives rise to smaller D coefficients Although less effective the extraction behavior of the C-pivot CMP analogs 13b-d shows more or less the same trend as the corresponding CMPO ligands 9b-e upon substitution of the carboxamide N-atom with different alkyl chains. The different malonamide ligands 17a-d and 18a,b are bad extractants, while N-alkylation makes them even worse. Potentiometric studies of CMP(O) and malonamide ligands in polymeric membranes on Pb2+, Cu2+, Ca2+, Mg2+, Na+, and K+ salts revealed that N-alkyl substituents increase the stability constants of ion-ionophore complexes compared to unsubstituted ligands. In polymeric membrane electrodes the ligands induce a selectivity pattern that differs significantly from the so-called Hofmeister series, giving the highest selectivity coefficients for UO22+ among all examined cations (Pb2+, Cu2+, Ca2+, Mg2+, Na+, K+). This study involved multiple reactions and reactants, such as 2,2′,2”-(2,4,6-Trimethylbenzene-1,3,5-triyl)triacetonitrile (cas: 16144-65-3Synthetic Route of C15H15N3).
2,2′,2”-(2,4,6-Trimethylbenzene-1,3,5-triyl)triacetonitrile (cas: 16144-65-3) belongs to nitriles. There has been no report on the microbial biosynthesis of nitriles and the physiological function of such enzymes, nor was it not even known whether aliphatic and aromatic nitriles are biological compounds or just petrochemicals. Alkyl nitriles are sufficiently acidic to undergo deprotonation of the C-H bond adjacent to the CN group.Strong bases are required, such as lithium diisopropylamide and butyl lithium. The product is referred to as a nitrile anion. Synthetic Route of C15H15N3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts