Dual-parameter correlation analysis of the redox potential data of 1-methyl-2-formyl-5-substituted pyrroles and their hydrazones was written by He, Hai Ying;Lin, Chen;Zhao, Cheng Xue;Jiang, Xi Kui. And the article was included in Chinese Chemical Letters in 2001.Safety of 5-Formyl-1-methyl-1H-pyrrole-2-carbonitrile The following contents are mentioned in the article:
By using 1-methyl-2-formyl-5-substituted pyrroles (1-Y), 1-methyl-2-formyl-5-substituted pyrrole phenylhydrazones (2-Y) and 1-methyl-2-formyl-5-substituted pyrrole (4-nitrophenyl)-hydrazones (3-Y) as model structures for N-containing heterocyclic aromatic compounds, correlation anal. of their redox potential data show that the transition states (TS) of the polarog. process are mainly affected by the polar effects, but spin-delocalization effects also exist. This study involved multiple reactions and reactants, such as 5-Formyl-1-methyl-1H-pyrrole-2-carbonitrile (cas: 81698-03-5Safety of 5-Formyl-1-methyl-1H-pyrrole-2-carbonitrile).
5-Formyl-1-methyl-1H-pyrrole-2-carbonitrile (cas: 81698-03-5) belongs to nitriles. The R-C-N bond angle in and nitrile is 180° which give a nitrile functional group a linear shape. Both the carbon and the nitrogen are sp hydridized which leaves them both with two p orbitals which overlap to form the two π bond in the triple bond. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Safety of 5-Formyl-1-methyl-1H-pyrrole-2-carbonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts