Kulkarni, Bheemashankar A.’s team published research in Tetrahedron Letters in 1999-07-23 | CAS: 87150-13-8

Tetrahedron Letters published new progress about Solid phase synthesis. 87150-13-8 belongs to class nitriles-buliding-blocks, name is 4-(5-Oxazolyl)benzonitrile, and the molecular formula is C10H6N2O, Application of 4-(5-Oxazolyl)benzonitrile.

Kulkarni, Bheemashankar A. published the artcileA solid-phase equivalent of van Leusen’s TosMIC, and its application in oxazole synthesis, Application of 4-(5-Oxazolyl)benzonitrile, the main research area is solid phase synthesis aryloxazole; oxazole aryl solid phase synthesis.

Polystyrene-SH resin, prepared from Merrifield resin in two steps, was converted to polystyrene-SO2-CH2-NC in three steps. This resin functions as a solid-phase equivalent of p-tolylsulfonylmethyl isocyanide (TosMIC). Thus, reaction with aromatic aldehydes and tetrabutylammonium hydroxide as base yields 5-aryloxazoles.

Tetrahedron Letters published new progress about Solid phase synthesis. 87150-13-8 belongs to class nitriles-buliding-blocks, name is 4-(5-Oxazolyl)benzonitrile, and the molecular formula is C10H6N2O, Application of 4-(5-Oxazolyl)benzonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts