Odani, Riko published the artcileCopper-Mediated Dehydrogenative Biaryl Coupling of Naphthylamines and 1,3-Azoles, SDS of cas: 87150-13-8, the main research area is dehydrogenative regioselective cross coupling naphthylamine azole picolinamide directing group; copper catalyst dehydrogenative regioselective cross coupling naphthylamine azole.
A copper-mediated dehydrogenative biaryl cross-coupling of naphthylamines and 1,3-azoles has been developed. The key to its success is the introduction of an N,N-bidentate coordination system based on the picolinamide directing group. The reaction proceeds smoothly without precious transition metal catalysts and provides highly π-extended heterobiaryls directly. E.g., in presence of Cu(OAc)2 and pivalic acid in mesitylene, dehydrogenative cross-coupling of N-(2-pyridylcarbonyl)-substituted 2-naphthylamine (I) with benzoxazole gave 73% II.
Journal of Organic Chemistry published new progress about Azoles Role: RCT (Reactant), RACT (Reactant or Reagent). 87150-13-8 belongs to class nitriles-buliding-blocks, name is 4-(5-Oxazolyl)benzonitrile, and the molecular formula is C10H6N2O, SDS of cas: 87150-13-8.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts