Li, Bryan’s team published research in Organic Syntheses in 2010 | CAS: 87150-13-8

Organic Syntheses published new progress about Bromination, regioselective. 87150-13-8 belongs to class nitriles-buliding-blocks, name is 4-(5-Oxazolyl)benzonitrile, and the molecular formula is C10H6N2O, Quality Control of 87150-13-8.

Li, Bryan published the artcileRegioselective C-4 bromination of oxazoles: 4-bromo-5-(thiophen-2-yl)oxazole, Quality Control of 87150-13-8, the main research area is regioselective bromination oxazole; Suzuki Miyaura coupling brominated oxazole.

A highly regioselective bromination at C-4 of 5-substituted oxazoles is described. The use of DMF as solvent and aging of the lithiated oxazole are critical to drive the equilibrium in favor of the acyclic isonitrile enolate, resulting in significantly improved C-4/C-2 regioselectivity. These 4-bromooxazoles were shown to be good Suzuki-Miyaura coupling partners with arylboronic acids.

Organic Syntheses published new progress about Bromination, regioselective. 87150-13-8 belongs to class nitriles-buliding-blocks, name is 4-(5-Oxazolyl)benzonitrile, and the molecular formula is C10H6N2O, Quality Control of 87150-13-8.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts