Kim, Michelle B. published the artcileSynthesis of Antimicrobial Natural Products Targeting FtsZ: (+)-Totarol and Related Totarane Diterpenes, Computed Properties of 5653-62-3, the main research area is totarol total synthesis diastereoselective cyclization; totaradiol total synthesis diastereoselective cyclization; totarolone total synthesis diastereoselective cyclization.
An efficient, convergent synthesis of totarol (I) by a diastereoselective epoxide/alkene/arene bicyclization is described. The reported synthesis enables the preparation of related diterpenes totaradiol(II) and totarolone (III) as well as previously unavailable derivatives that exhibit comparable inhibition of the bacterial cell division protein FtsZ.
Organic Letters published new progress about Cyclization, stereoselective. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Computed Properties of 5653-62-3.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts