Chapas, Richard B. published the artcileNef-type transformation in basic solution, HPLC of Formula: 34133-58-9, the main research area is Nef reaction nitro nitrile ketone; mechanism aromatic Nef reaction.
The replacement of the nitro group of o-O2NC6H4CN to give 2-hydroxyisophthalonitrile (I) (by the action of NaCN in Me2SO) occurred via a Nef-type reaction of the cyanide ion adduct of the nitro nitrile. The normal 2nd product of the Nef reaction, N2O was produced in yield comparable to that of I. P-O2NC6H4CN and p-O2NC6H4COPh reacted similarly. The mechanism was discussed.
Journal of Organic Chemistry published new progress about Nitro compounds Role: PRP (Properties). 34133-58-9 belongs to class nitriles-buliding-blocks, name is 4-Hydroxyisophthalonitrile, and the molecular formula is C8H4N2O, HPLC of Formula: 34133-58-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts