Ruan, Jiwu published the artcile[2.2]Paracyclophane-based monophosphine ligand for palladium-catalyzed cross-coupling reactions of aryl chlorides, SDS of cas: 204078-32-0, the main research area is paracyclophane monophosphine JPhos ligand preparation amination coupling catalyst; aryl chloride paracyclophane monophosphine palladium amine Buchwald Hartwig amination; aminobenzene preparation; palladium paracyclophane monophosphine aryl chloride boronic Suzuki Miyaura coupling; biaryl preparation; Buchwald Hartwig amination Suzuki Miyaura coupling catalyst JPhos palladium.
A new [2.2]paracyclophane-based electron-rich and sterically bulky monophosphine ligand has been synthesized by an efficient and straightforward method. When combined with palladium, this ligand shows excellent performance in the Buchwald-Hartwig amination and Suzuki-Miyaura coupling reactions of various aryl chlorides. In both types of reactions, ortho-substituted, deactivated aryl chlorides are shown to be viable substrates. However, the Suzuki-Miyaura coupling appears to be easier, with palladium loading at 0.1 mol% being feasible.
Organic & Biomolecular Chemistry published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 204078-32-0 belongs to class nitriles-buliding-blocks, name is 2-Morpholinobenzonitrile, and the molecular formula is C11H12N2O, SDS of cas: 204078-32-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts