Rahimzadeh, Golnaz published the artcileImprovement of the Van Leusen reaction in the presence of β-cyclodextrin as a green and efficient catalyst for synthesis of oxazoles in water, Quality Control of 87150-13-8, the main research area is tosylmethylisocyanide aryl aldehyde reusable cyclodextrin green Van Leusen heterocyclization; aryl oxazole preparation.
An efficient approach for the synthesis of oxazoles through the Van Leusen reaction in the presence of β-cyclodextrin was described. In aqueous medium using β-cyclodextrin as a supramol. catalyst, tosylmethyl isocyanide was deprotonated by triethylamine and subsequently underwent an addition/cyclization reaction with aldehydes to produce corresponding oxazoles in excellent yields. This protocol improved the Van Leusen reaction with the use of catalytic amounts of base at low temperature in green media.
Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 87150-13-8 belongs to class nitriles-buliding-blocks, name is 4-(5-Oxazolyl)benzonitrile, and the molecular formula is C10H6N2O, Quality Control of 87150-13-8.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts