Primas, Nicolas published the artcileSynthesis of 2-TIPS-oxazol-5-ylboronic acid pinacol ester: efficient route to 5-(het)aryloxazoles via Suzuki cross-coupling reaction, Formula: C10H6N2O, the main research area is silyloxazolylboronic pinacol ester preparation Suzuki coupling reaction aryl halide; oxazole aryl heteroaryl preparation.
A facile synthetic route to the new 2-TIPS-oxazol-5-ylboronic acid pinacol ester was described herein. Its reactivity toward Suzuki cross-coupling reaction was studied to provide various 5-(het)aryloxazoles. E.g., Suzuki cross-coupling reaction of 2-TIPS-oxazol-5-ylboronic acid pinacol ester I with 4-MeOC6H4I gave 79% 5-aryloxazole II. A wide range of functions on the aryl moiety are tolerated.
Tetrahedron published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 87150-13-8 belongs to class nitriles-buliding-blocks, name is 4-(5-Oxazolyl)benzonitrile, and the molecular formula is C10H6N2O, Formula: C10H6N2O.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts