Rina, Yesmin Akter published the artcileDouble Hydrophosphorylation of Nitriles Catalyzed by Rare-Earth-Metal Lanthanum, Safety of Picolinonitrile, the main research area is hydrophosphorylation aromatic nitrile hydrophosphonate preparation phosphono amidophosphate lanthanum catalyst; lanthanum dimethylbenzylamine catalyst double hydrophosphorylation nitrile preparation phosphoryl amidophosphate.
A high-yielding and atom-efficient protocol for the double hydrophosphorylation of aromatic nitriles using a lanthanum-based N,N-dimethylbenzylamine complex (La(DMBA)3) as a precatalyst is reported, giving α-phosphonylated N-benzylphosphoramidates ArCH[P(O)(OEt)2]NHP(O)(OEt)2 (3a-v; Ar = substituted Ph, 2-naphthyl, pyridyl) with high yields and chemoselectivities. This method provides a straightforward and convenient approach for the synthesis of biol. important organophosphorus compounds known as N-(α-phosphoryl)amidophosphates in good to excellent yields. Nitriles with a broad range of addnl. functionality were tolerated, including those with halides, ethers, amines, and pyridyl groups.
Journal of Organic Chemistry published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Safety of Picolinonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts