Master, Hoshang E. published the artcileDesign and synthesis of low molecular weight compounds with complement inhibition activity, Recommanded Product: 2,3-Dimethoxybenzonitrile, the main research area is tetrazole derivative preparation complement inhibitor; complement inhibitor phenylacrylic acid derivative preparation.
An attempt was made to synthesize a series of noncytotoxic low mol. weight compounds of varying substitutions and functionalities having pharmacophore activity like carbonyl compounds, carboxylic acid and bioisosteres like tetrazole and Ph acrylic acid. The in vitro assay of these analogs for the inhibition of complement activity revealed significant inhibitory activity for varying substituents and, particularly, for bioisosteres, i.e., tetrazole and Ph acrylic acid derivatives
Bioorganic & Medicinal Chemistry published new progress about Structure-activity relationship (complement-inhibiting). 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Recommanded Product: 2,3-Dimethoxybenzonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts