Tyagi, Aparna published the artcileBroensted acid-catalyzed epoxide ring-opening using amine nucleophiles: A facile access to β-amino alcohols, Quality Control of 1885-29-6, the main research area is amino alc beta synthesis; styrene oxide epoxide ring opening aniline Broensted acid catalyst; ring opening reaction mechanism kinetics Hammett equation; Suzuki Miyaura Cross coupling reaction; aniline; metal-free; phenyl oxirane; β-amino alcohols.
A mild, efficient, and metal-free synthetic protocol for the synthesis of β-amino alcs. is reported. The reaction proceeds at room temperature with only 0.5 mol % catalyst loading and affords β-amino alc. derivatives in excellent yield. This protocol is well-tolerated by a wide range of styrene oxide and aniline derivatives A notably efficacious gram-scale synthesis is also reported with a high TON=842. Further, the Hammett correlation study was also performed to identify the rate-determining step.
Chemistry – An Asian Journal published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Quality Control of 1885-29-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts