Tian, Jun-Jie published the artcileIntramolecular Cyclizations of Vinyl-Substituted N,N-Dialkyl Arylamines Enabled by Borane-Assisted Hydride Transfer, Quality Control of 1885-29-6, the main research area is arylamine dialkyl vinyl borane hydride transfer cyclization catalyst; tetrahydrobenzoquinoline preparation.
Catalytic amounts of B(C6F5)3 have been found to be able to promote the intramol. cyclization of vinyl-substituted N,N-dialkyl arylamines to afford nitrogen-containing heterocycles I (R = Me, Bn, n-pentyl; R1 = H, Ph, n-Bu; R2 = Ph, 4-EtC6H4, 3-MeC6H4, Me, n-Pr, etc.). Our mechanistic studies indicate the reaction is initiated by abstraction of an α-hydride from an N-alkyl substituent by B(C6F5)3, which is followed by cyclization, and is concluded by delivery of the hydride to the cyclic cationic intermediate. The dual roles of B(C6F5)3, first as an oxidant and then as a hydride-carrying reductant, have enabled a rare redox-neutral cyclization process between a sp3 carbon and an electron-rich olefin without using a transition metal or an external oxidant.
ACS Catalysis published new progress about Boranes Role: CAT (Catalyst Use), USES (Uses). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Quality Control of 1885-29-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts