Shuai, Bin published the artcileNickel-Catalyzed Favorskii-Type Rearrangement of Cyclobutanone Oxime Esters to Cyclopropanecarbonitriles, Quality Control of 97009-67-1, the main research area is cyclopropanecarbonitrile preparation; cyclobutanone oxime ester Favorskii rearrangement nickel catalyst.
A nickel-catalyzed base-promoted rearrangement of cyclobutanone oxime esters I (R1 = H, 4-tert-butyphenyl, 6-methoxynaphthalen-2-yl, phenylselanyl, etc.; R2 = H, Me, Ph; R3 = H, 2-naphthyl, 4-tert-butylphenyl, Ph, etc.; R2R3 = 1-adamantyl, 4-phenylcyclohexyl, cycloheptyl, etc.) to cyclopropanecarbonitriles II was developed. The ring opening of cyclobutanone oxime esters I occurs at the sterically less hindered side. A base-promoted nickelacyclobutane intermediate, formed in situ, is assumed to be involved in the formation of the product.
Synlett published new progress about Cyclopropanes Role: SPN (Synthetic Preparation), PREP (Preparation) (carbonitriles). 97009-67-1 belongs to class nitriles-buliding-blocks, name is 1-(4-Fluorophenyl)cyclopropanecarbonitrile, and the molecular formula is C10H8FN, Quality Control of 97009-67-1.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts