Pathaw, Larica’s team published research in Journal of Molecular Structure in 2020-05-05 | CAS: 100-70-9

Journal of Molecular Structure published new progress about Coordination sphere. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Safety of Picolinonitrile.

Pathaw, Larica published the artcileSynthesis, crystal structure, bovine serum albumin binding studies of 1,2,4-triazine based copper(I) complexes, Safety of Picolinonitrile, the main research area is pyridyltriazole copper complex preparation crystal mol structure; bovine serum albumin binding copper pyridyltriazole complex.

A series of new copper complexes have been synthesized and completely characterized by pivotal anal. techniques. The coordination geometry around copper(I) complex was best described as distorted tetrahedral geometry. The binding of bovine serum albumin with Cu(I) complexes are also been investigated. The Stern-Volmer anal. on quenching data exhibits the presence of the static quenching mechanism. The binding constants were calculated using modified Stern-Volmer, Lineweaver-Burk and Scatchard plots. All the complexes exhibit the binding constants in the order of 104. Thus, these results can contribute to the development of Cu(I) based drugs.

Journal of Molecular Structure published new progress about Coordination sphere. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Safety of Picolinonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts