Fu, Zhengjiang published the artcileConversions of aryl carboxylic acids into aryl nitriles using multiple types of Cu-mediated decarboxylative cyanation under aerobic conditions, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is aryl nitrile preparation green chem; malononitrile aryl carboxylic acid decarboxylative cyanation copper catalyst; azodimethylbutyronitrile aryl carboxylic acid decarboxylative cyanation copper catalyst.
Here, used malononitrile or AMBN as a cyanating agent to develop efficient and practical protocols for Cu-mediated decarboxylative cyanations, under aerobic conditions, of aryl carboxylic acids RC(O)OH (R = 2-nitrophenyl, 2,4,6-trimethoxyphenyl, 3-methyl-1-benzothiophen-2-yl, etc.) bearing nitro and methoxyl substituents at the ortho position as well as of heteroaromatic carboxylic acids. These protocols involved economical methods to synthesize value-added aryl nitriles RCN from simple and inexpensive raw materials. Further diversification of the 2-nitrobenzonitrile product was performed to highlight the practicality of the protocols.
Organic & Biomolecular Chemistry published new progress about Aromatic nitriles Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts