Delcaillau, Tristan published the artcileNickel-Catalyzed Reversible Functional Group Metathesis Between Aryl Nitriles And Aryl Thioethers, HPLC of Formula: 100-70-9, the main research area is aryl nitrile preparation; thioether aryl nitrile reversible functional group metathesis nickel catalyst; aromatic thioether preparation; nitrile aryl thioether reversible functional group metathesis nickel catalyst.
A new functional group metathesis between aryl nitriles and aryl thioethers via nickel/dcype catalysis to achieve fully reversible transformation to afford aryl nitriles R-CN [R = 4-tBuC6H4, 3-FC6H4, 2-naphthyl, etc.] and aryl thioethers R1-SMe [R1 = 4-NCC6H4, 2-pyridyl, 4-F3CC6H4, etc.] in good to excellent yields was reported. Furthermore, the cyanide and thiol-free reaction showed high functional-group tolerance and great efficiency for late-stage derivatization of com. mols. Finally, synthetic applications demonstrated its versatility and utility in multistep synthesis.
Journal of the American Chemical Society published new progress about Metathesis. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, HPLC of Formula: 100-70-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts