On August 1, 2007, Rachid, Zakaria; Katsoulas, Athanasia; Williams, Christopher; Larroque, Anne-Laure; McNamee, James; Jean-Claude, Bertrand J. published an article.Related Products of 34662-29-8 The title of the article was Optimization of novel combi-molecules: Identification of balanced and mixed bcr-abl/DNA targeting properties. And the article contained the following:
Steps toward the identification of combi-mols. with strong abl tyrosine kinase (TK) inhibitory property and significant DNA damaging potential are described. The optimized combi-mol. (I) was shown to induce approx. twofold stronger abl TK inhibitory activity than Gleevec and high levels of DNA damage in chronic myelogenous leukemic cells. The experimental process involved the reaction of 3-Chloro-4-nitrobenzonitrile(cas: 34662-29-8).Related Products of 34662-29-8
The Article related to gleevec analog preparation abl tyrosine kinase inhibitor antitumor leukemia, Pharmacology: Structure-Activity and other aspects.Related Products of 34662-29-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts