On August 31, 2002, Goker, Hakan; Kus, Canan; Boykin, David W.; Yildiz, Sulhiye; Altanlar, Nurten published an article.Formula: C7H3ClN2O2 The title of the article was Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5-carbonitriles and their potent activity against Candida species. And the article contained the following:
New 2-substituted-phenyl-1H-benzimidazole-5-carboxylic acids, ethyl-5-carboxylate, -5-carboxamides,-5-carboxaldehyde, -5-chloro-, -5-trifluoromethyl, and -5-carbonitriles, -6-carbonitrile were prepared and evaluated in vitro against Candida species. The cyano substituted compounds exhibited the greatest activity with MIC values of 3.12 μg/mL, values similar to that of fluconazole. The experimental process involved the reaction of 3-Chloro-4-nitrobenzonitrile(cas: 34662-29-8).Formula: C7H3ClN2O2
The Article related to substituted phenyl benzimidazole carbonitrile candida activity, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Formula: C7H3ClN2O2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts