On June 10, 2010, Canne Bannen, Lynne; Chan, Diva Sze-Ming; Gu, Xiao-Hui; Mac, Morrison B.; Ng, Stephanie; Wang, Tie-Lin; Wang, Yong; Xu, Wei published a patent.Application of 34662-29-8 The title of the patent was Imidazo[1,2a]pyridine derivatives, their use as S1P1 agonists and methods for their production. And the patent contained the following:
The invention is directed to compounds of formula I as well as methods of making and using the compounds Compounds of formula I wherein R1 is H, halo, CN, C1-6 alkoxy, amino, etc.; R2 is H, Me, and MeO; R3 is H, C1-6 alkyl, C1-6 alkylsulfonyl, halo, C1-6 haloalkyl, etc.; R4 is H and C1-6 alkyl; A is 5-membered heteroarylene; R5 is (un)substituted Ph and (un)substituted heteroaryl; and stereoisomers, mixtures of isomers, and pharmaceutically acceptable salts thereof, are claimed. Example compound II was prepared by a multistep procedure (procedure given). All the invention compounds were evaluated for their S1P1 agonistic activity. The experimental process involved the reaction of 3-Chloro-4-nitrobenzonitrile(cas: 34662-29-8).Application of 34662-29-8
The Article related to imidazopyridine preparation s1p1 agonist treatment disease, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Application of 34662-29-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts