On December 4, 1997, Mitchell, Glynn; Smith, Stephen Christopher published a patent.Application of 13544-06-4 The title of the patent was Preparation of 1-aminoacetylindolines and analogs as herbicides. And the patent contained the following:
RC(:W1)CR1R2YC(:W2)ZR3 [I; R = (un)substituted indolino; R1,R2 = H or alkyl; R3 = H or (halo)aliphatyl, etc.; W1,W2 = O or S; Y = O or NR4; R4 = H, alkoxy, aliphatyl; Z = NR5 or CR6R7; R5-R7 = H or aliphatyl; R4R5 = CH2CH2, CH:CH, COCO, CH2CO; R6R7 = atoms to complete a carbocyclic ring] were prepared Thus, (EtO2CCH2)2NH was N-acylated by Me3CNCO and the product cyclized to give, after saponification, 2,4-dioxo-3-tert-butylimidazolidine-1-acetic acid which was chloridnated and the product amidated by 6-chloroindoline to give title compound II. Data for biol. activity of I were given. The experimental process involved the reaction of 2-(2-Nitro-4-(trifluoromethyl)phenyl)acetonitrile(cas: 13544-06-4).Application of 13544-06-4
The Article related to aminoacetylindoline preparation herbicide, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Application of 13544-06-4
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts