On February 20, 1985, Koeckritz, Peter; Liebscher, Alexander published a patent.Computed Properties of 2510-01-2 The title of the patent was N,N,1,2,3-Pentasubstituted 4-amino-1-cyano-1,3-butadiene. And the patent contained the following:
R2R3NCH:CR1CR:CXCN [R,R1 = alkyl, aryl; RR1 = (CH2)n (n = 3-5); R2, R3 = alkyl, aryl; R2R3 = (CH2)4, (CH2)5, (CH2)2O(CH)2; X = CN, carbonyl such as acyl, alkoxycarbonyl, H2NCO, NO2, aryl], useful as synthons for pharmaceuticals were prepared by reaction of R1CH2CR:CXCN with HC(OR4)3 (R4 = alkyl) and HNR2R3 in the presence of acidic condensation agent by 8 methods. A mixture of 2-O2NC6H4CO2H and 0.01 mol HNPhMe was treated with 0.015 mol HC(OEt)3 and 0.01 mol Me2C:C(CN)2 and the mixture refluxed 30 min. to give 65% MePhNCH:CHCMe:C(CN)2. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Computed Properties of 2510-01-2
The Article related to aminocyanobutadiene pharmaceutical synthon, cyanobutadiene amino pharmaceutical synthon, butadiene aminocyano pharmaceutical synthon, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Nitriles, Isonitriles, and Acyl Cyanides and other aspects.Computed Properties of 2510-01-2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts