On June 30, 2011, Jain, Shubha; Bhimireddy, Nagi Reddy; Kolisetty, Sambasiva Rao published an article.Computed Properties of 75629-62-8 The title of the article was L-proline catalyzed Knoevenagel condensation: synthesis of some new indole derivatives and biological activities. And the article contained the following:
Knoevenagel condensation of various heteroaromatic aldehydes with active methylene compounds like malononitrile, Et cyanoacetate, barbituric acid, meldrum’s acid and dimedone proceeds smoothly with stirring under conventional heating. Twenty Knoevenagel condensation products were synthesized with excellent yields. The indole derivatives, e.g., I, were also screened for their antibacterial activity. The work-up procedure is very simple and the products do not require further purification The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).Computed Properties of 75629-62-8
The Article related to indole substituted preparation bacterial infection antibacterial activity, indolecarboxaldehyde active methylene knoevenagel condensation proline catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Computed Properties of 75629-62-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts