Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Recommanded Product: 4-(2-Bromoacetyl)benzonitrile.
Zhou, Jinlei;Shi, Xiaotian;Zheng, Huitao;Chen, Guangxian;Zhang, Chen;Liu, Xiang;Cao, Hua research published 《 Deconstructive Cycloaromatization Strategy toward N,O-Bidentate Ligands from Indolizines and Cyclopropenones》, the research content is summarized as follows. Here, an unprecedented approach for the construction of polyaryl N,O-bidentate derivatives via the merging of ring deconstruction with cycloaromatization of indolizines and cyclopropenones was reported. Without any catalysts, this method could deliver a series of polyaryl 2-(pyridin-2-yl)phenols I [R1 = H, 4-Me, 5-Et, etc.; R2 = Me, cyclopropyl, Ph, etc.; Ar = Ph, 4-MeC6H4, 3-MeC6H4, 4-MeOC6H4, 2-thienyl] in excellent yields. In addition, N,O-bidentate organic BF2 complexes, e.g., II, could also be constructed via this one-pot protocol.
20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Recommanded Product: 4-(2-Bromoacetyl)benzonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts