Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Product Details of C4H5NO2.
Zhang, Wei;Xiang, Shiqun;Fan, Weibin;Jin, Jiang;Li, Yinghua;Huang, Deguang research published 《 A three-component iodine-catalyzed oxidative coupling reaction: a heterodifunctionalization of 3-methylindoles》, the research content is summarized as follows. A metal-free method for the synthesis of heterodifunctional indole derivatives was developed through TBHP/KI-mediated oxidative coupling. The reaction constructed C-O and C-C bonds in succession with the help of tert-Bu peroxy radicals generated by the TBHP/KI catalytic system, enabling the direct realization of the heterodifunctionalization of indole in one pot. The product of this reaction was a novel heterodifunctional compound This work might provided a new effective method for the synthesis of polycyclic indole compounds
Product Details of C4H5NO2, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts