Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. HPLC of Formula: 105-34-0.
Yang, Jianjing;Zeng, Ting;Yan, Kelu;Qin, Zonghui;Wen, Jiangwei research published 《 Direct Synthesis of Alkylthioimidazoles: One-Pot Three-Component Cross-Coupling Mediated by Paired Electrolysis》, the research content is summarized as follows. The direct synthesis of alkylthioimidazoles was initially accomplished via a one-pot three-component cross-coupling mediated by a paired electrolysis strategy using non-activated chloroalkane as the alkylating agent. This protocol provides a straightforward method for the preparation of alkylthioimidazoles by employing water as the co-solvent at room temperature without any exogenous-oxidants and metal catalysts. Inactivated primary, secondary, tertiary haloalkanes and various isothiocyanates was compatible with the established conditions to obtain the corresponding products with a moderate yield. The mechanism of this one-pot three-component cross-coupling reaction undergoes a radical process mediated by paired electrolysis.
HPLC of Formula: 105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts