Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Quality Control of 105-34-0.
Wu, Feng;Du, Juan;Liu, Na;Xu, Jie;Xue, Bing research published 《 Potassium-doped carbon nitride supported on SBA-15 for enhanced catalytic Knoevenagel condensation under mild conditions》, the research content is summarized as follows. Knoevenagel condensation reaction is an important reaction for the manufacture of α,β-unsaturated carbonyl compounds Traditional base catalysts suffer from the disadvantage in catalyst-product separation Herein, potassium-doped carbon nitride materials supported on SBA-15 (CN/SBA15-KCl) have been prepared through a one-pot calcination method. The characterization results of N2 adsorption-desorption, small-angle XRD, TEM, and SEM revealed that the ordered mesostructures of SBA-15 had been preserved after the loading of carbon nitride and KCl, and nitrogen and potassium species were dispersed on the surface of SBA-15 support. As solid bases, the CN/SBA15-KCl materials demonstrated high and steady catalytic performances in Knoevenagel condensation. Under 50°C of reaction temperature, the optimized conversion of benzaldehyde was up to 74% at 4 h of reaction time, much higher than other carbon-nitride-based materials. The incorporation of potassium has been proved to enhance the basic strength of CN/SBA15, and therefore improved the catalytic activity.
105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., Quality Control of 105-34-0
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts