Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Electric Literature of 1835-49-0.
Wang, Yan;Chen, Yaqi;Bian, He;Sun, Yawei;Zhu, Lijun;Xia, Daohong research published 《 Highly selective and sensitive chiral recognition to deoxynucleosides by calixarene oligomers modified silver nanoparticles》, the research content is summarized as follows. Efficient enantiomeric sensing to deoxynucleosides by a simple method is of great importantance and remains a challenge in biochem. field. In this paper, three chiral calixarene oligomers (CA[n]P, n=4, 6, 8) were synthesized and characterized by Fourier Transform IR Spectroscopy, UV-vis spectrophotometry, CD spectroscopy , X-ray Powder Diffraction, XPS, Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry, 19F NMR and SEM. After that, the chiral calixarene oligomers capped silver nanoparticles (CA[n]P-Ag NPs, n=4, 6, 8) were prepared and characterized by FT-IR, UV-vis spectrophotometry, CD and dynamic light scattering. By using the as prepared CA[n]P-Ag NPs (n=4, 6, 8), highly selective and sensitive chiral recognition to deoxynucleosides was realized and demonstrated by UV-vis and CD. The color of the CAP-Ag NPs changes from yellow to red in the presence of β-L-2′-deoxycytidine (L-dC) or β-L-2′-deoxythymidine (L-dT) at a certain time, but not of their corresponding enantiomer β-D-2′-deoxycytidine (D-dC) or β-L-2′-deoxythymidine (D-dT). Moreover, the chiral recognition ability of CA[n]P-Ag NPs (n=4, 6, 8) toward L-deoxynucleosides was found to be in the order of CA[8]P-Ag NPs>CA[6]P-Ag NPs>CA[4]P-Ag NPs. This convenient method shows forceful prospect in developing biochem. sensors and has the potential application in enantiomeric recognition and separation of deoxynucleosides.
Electric Literature of 1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts