Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Product Details of C9H5N.
Su, Lebin;Xie, Shimin;Dong, Jianyu;Pan, Neng;Yin, Shuang-Feng;Zhou, Yongbo research published 《 Copper-Catalyzed 6-endo-dig Cyclization-Coupling of 2-Bromoaryl Ketones and Terminal Alkynes toward Naphthyl Aryl Ethers in Water》, the research content is summarized as follows. The cyclization-coupling reaction of 2-bromoaryl ketones 2-Br-4-R-5-R1C6H2C(O)Me (R = H, Cl, F, MeO; R1 = H, Cl, Me), 1-(pyridin-3-yl)ethan-1-one and terminal alkynes R2CCH (R2 = Ph, 4-bromophenyl, pyridin-3-yl, etc.) is first realized by copper catalysis, which produces polyfunctional naphthyl aryl ethers I (X = CH, N) in moderate to excellent yields with broad substrate scope and good functional group tolerance. This reaction proceeds via 6-endo-dig cyclization and C(sp2)-O coupling using green H2O as the unique solvent and 5-bromopyrimidin-2-amine as the critical additive. Mechanistically, a unique Cu(III)-acetylide probably is the key intermediate, which allows exclusive 6-endo-dig selectivity.
3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.
4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Product Details of C9H5N
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts