Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Category: nitriles-buliding-blocks.
Sergeev, Pavel G.;Khrustalev, Victor N.;Nenajdenko, Valentine G. research published 《 Synthesis of Pyridazin-3(2H)-one Derivatives by the Reaction of CH-Acids with Dichlorodiazadienes》, the research content is summarized as follows. The reactions of 4,4-dichloro-1,2-diazabuta-1,3-dienes with di-Me malonate, cyanoacetic esters and Et acetoacetate provided straightforward access to highly functionalized pyridazine derivatives The approach was found to be very general for the highly efficient synthesis of various pyridazine derivatives , e.g., I, which can be isolated in moderate to excellent yields. The possibility of their subsequent functionalization was demonstrated. Moreover, the absorption characteristics in the UV/Vis-range and luminescence were studied for all synthesized compounds
105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., Category: nitriles-buliding-blocks
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts