Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. Related Products of 3032-92-6.
Mo, Xueling;Huang, Han;Zhang, Guozhu research published 《 Tetrasubstituted Carbon Stereocenters via Copper-Catalyzed Asymmetric Sonogashira Coupling Reactions with gem-Dihaloketones and α-Bromo-γ-lactams》, the research content is summarized as follows. The construction of chiral tetrasubstituted carbon stereocenters is an ongoing challenge in synthetic organic chem. due to its prevalence in multiple disciplines. One efficient approach is the catalytic asym. C-C coupling reactions of a readily available racemic tertiary alkyl electrophile by simple organic nucleophiles. While a variety of secondary alkyl halides succeeded in asym. Cu-catalyzed Sonogashira-type cross-coupling reactions with diverse alkynes, tertiary alkyl halides have rarely been used in this kind of coupling reaction. Herein, tertiary bromides can serve as efficient coupling partners in copper/bisoxazoline Ph amine (BOPA)-catalyzed asym. alkynylation is demonstrated, leading to synthetically and medicinally valuable tertiary C-F stereocenters and all-carbon quaternary stereocenters.
3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.
4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Related Products of 3032-92-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts