Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. Related Products of 3032-92-6.
Ma, Peng;Wang, Yuhang;Wang, Jianhui research published 《 Copper-Catalyzed Domino Three-Component Benzannulation: Access to Isoquinolines》, the research content is summarized as follows. The authors report herein the synthesis of isoquinolines through a Cu(I)-catalyzed domino reaction. During this transformation, three mols. of terminal alkynes, 2-bromoaryl aldehydes (ketones), and acetamide react together, in a sequence including Sonogashira coupling, condensation, 6-endo-dig cyclization, elimination of HOAc ,and hydrolysis. In this reaction, isoquinolines with broad functional group tolerance were successfully obtained by using acetamide as N source, which provides an alternative to odorous and toxic amines.
Related Products of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.
4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts