Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Recommanded Product: 4-Ethynylbenzonitrile.
Lokolkar, Manjunath S.;Mane, Pravin A.;Dey, Sandip;Bhanage, Bhalchandra M. research published 《 Synthesis of 2-Substituted Indoles by Pd-Catalyzed Reductive Cyclization of 1-Halo-2-nitrobenzene with Alkynes》, the research content is summarized as follows. An effective process for synthesizing 2-substituted indoles in a one-pot tandem reaction of 1-halo-2-nitrobenzene and terminal alkynes through addition/reductive cyclization is presented. This protocol involves a Sonogashira-type coupling reaction followed by reductive cyclization employing dppf (1,1′-bis(diphenylphosphino)ferrocene) ligated Pd dithiolate complex as a catalyst and Zn as an inexpensive reductant. This efficient and tandem process tolerates broad functional groups with moderate to good yields. The gram-scale synthesis of 2-substituted indole has also been demonstrated. This protocol provides an alternative route for the synthesis of 2-substituted indoles.
Recommanded Product: 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.
4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts