Lin, Hui-Shu team published research in Advanced Synthesis & Catalysis in 2022 | 3032-92-6

Synthetic Route of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Synthetic Route of 3032-92-6.

Lin, Hui-Shu;Pan, Yong-Zhou;Tian, Yu-Hong;Pan, Ying-Ming;Wang, Xu research published 《 Palladium-Catalyzed Tandem Cyclization of 2-(2 Ethynylphenyl)acetonitriles and Isocyanides: Access to Indeno[2,1-b]pyrroles》, the research content is summarized as follows. A palladium-catalyzed tandem cyclization of 2-(2-ethynylphenyl)acetonitriles I (R1 = Ph, naphthalen-2-yl, thiophen-3-yl, etc.) with isocyanides CNR2 (R2 = tert-Bu, cyclohexyl, adamantan-1-yl, etc.) has been developed. Various indeno[2,1-b]pyrroles II were prepared in 55%-82% yields under air atm. at 100°C. The key to the success of this protocol is construction of new C-C and C-N bonds via the orderly insertion of isocyanides.

Synthetic Route of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts