On December 7, 2009, Xiong, Xiao-Feng; Jia, Zhi-Jun; Du, Wei; Jiang, Kun; Liu, Tian-Yu; Chen, Ying-Chun published an article.Application In Synthesis of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile The title of the article was Merging chiral organocatalysts: enantio- and diastereoselective direct vinylogous Mannich reaction of alkylimines. And the article contained the following:
An enantio- and diastereoselective direct vinylogous Mannich reaction of α,α-dicyanoolefins and N-sulfonyl alkylimines has been developed. Using the catalysis of a new family of bifunctional organocatalysts merging chiral BINOL and 9-amino-9-deoxyepi-cinchona alkaloid skeletons, chiral β-, δ- or γ-amino compounds could be efficiently derived. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Application In Synthesis of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile
The Article related to cinchona alkaloid binol derived chiral bifunctional organocatalyst preparation, dicyanoolefin sulfonyl alkylimine chiral bifunctional organocatalyst vinylogous mannich addition, amino dicyanoolefin derivative stereoselective preparation and other aspects.Application In Synthesis of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts