On November 26, 1986, Koeckritz, Peter; Liebscher, Juergen; Schmidt, Ludmilla published a patent.Computed Properties of 2510-01-2 The title of the patent was Preparation of 2,3,N,N-tetrasubstituted-1,1-dicyano-4-amino-1,3-butadienes useful as intermediates for analgesics, etc.. And the patent contained the following:
The title compounds (R2)2NCH:CR1CR:C(CN)2 [I; R, R1 = H, (un)substituted alkyl or alkenyl, aryl, heteroaryl; RR1 = (CH2)3-5, CH2NH(CH2)2, benzo-condensed alkenylene, e.g., o-C6H4CH2CH2; R2 = alkyl; R2R2 = (CH2)4-5, (CH2)2O(CH2)2, (CH2)2NH(CH2)2], useful as intermediates for heterocyclic compounds with antiphlogistic, analgesic, or antirheumatic activity, are prepared by reacting R1CH2CR:C(CN)2 with (R2)2NCH(OR3)2 (R3 = alkyl) in the presence of a protonic acid. A solution of Me2C:C(CN)2 in AcOH was treated with (R2)2NCH(OMe)2 [R2R2 = (CH2)2O(CH2)2] and the mixture was warmed to boiling to give 81% I [R = Me, R1 = H, R2R2 = (CH2)2O(CH2)2]. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Computed Properties of 2510-01-2
The Article related to analgesic intermediate aminocyanobutadiene preparation, antiphlogistic intermediate aminocyanobutadiene preparation, antirheumatic intermediate aminocyanobutadiene preparation, heterocycle intermediate aminocyanobutadiene preparation, aminocyanobutadiene preparation heterocycle intermediate, cyanobutadiene amino preparation heterocycle intermediate and other aspects.Computed Properties of 2510-01-2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts