Ang, Wei Jie; Chng, Yong Sheng; Lam, Yulin published an article in 2015, the title of the article was Fluorous bispidine: a bifunctional reagent for copper-catalyzed oxidation and Knoevenagel condensation reactions in water.Product Details of 75629-62-8 And the article contains the following content:
Fluorous bispidine-type ligands, I [R = 4-CF3(CF2)7(CH2)3C6H4CH2, (CH2)2(CF2)7CF3] and II [R1 = (CH2)2(CF2)7CF3] has been developed to facilitate its recovery and reusability and to demonstrate its bifunctional property as a ligand and base in copper-catalyzed aerobic oxidation, the Knoevenagel condensation and tandem oxidation/Knoevenagel condensation in water under mild conditions. Application of the fluorous ligand was also extended to the surfactant-free copper-catalyzed allylic and benzylic sp3 C-H oxidation reaction in water. The fluorous ligands could be recovered using F-SPE with recovery ranging from 91-97% and could be reused five times with little loss of activity. The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).Product Details of 75629-62-8
The Article related to bispidine fluorous preparation, carbonyl compound preparation green chem, alc aerobic oxidation copper catalyst fluorous bispidine, alkene preparation green chem, active methylene carbonyl compound knoevenagel condensation copper fluorous bispidine and other aspects.Product Details of 75629-62-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts