Zheng, Yi; Liu, Wenbo; Ren, Yun-Lai; Guo, Yinggang; Tian, Xinzhe published their research in ChemistrySelect in 2021. The article was titled 《Copper-Catalyzed Cleavage of Aryl C(OH)-C Bonds to Access Aryl Nitriles》.Product Details of 1194-02-1 The article contains the following contents:
It was found that aryl nitriles could be synthesized by cleavage of aryl C(OH)-C bonds in the presence of oxygen gas, (NH4)2CO3 and Cu(OAc)2. The present protocol allowed various secondary aryl alcs. to underwent the present transformation to give aryl nitriles in low to high yields. Lignin-related β-O-4 and β-1 linkages could be converted to benzonitriles under the present conditions, which provides an avenue to obtain value nitrile products via fragmentation of lignin. The experimental part of the paper was very detailed, including the reaction process of 4-Fluorobenzonitrile(cas: 1194-02-1Product Details of 1194-02-1)
4-Fluorobenzonitrile(cas: 1194-02-1) is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.Product Details of 1194-02-1
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts