In 2019,Chem included an article by Zhao, Da; Xu, Peng; Ritter, Tobias. Category: nitriles-buliding-blocks. The article was titled 《Palladium-Catalyzed Late-Stage Direct Arene Cyanation》. The information in the text is summarized as follows:
The first general late-stage aryl C-H cyanation with broad substrate scope and functional-group tolerance was reported. The reaction was enabled by a dual-ligand combination of quinoxaline and an amino acid-derived ligand. The method was applicable to direct cyanation of several marketed small-mol. drugs, common pharmacophores and organic dyes.4-Fluorobenzonitrile(cas: 1194-02-1Category: nitriles-buliding-blocks) was used in this study.
4-Fluorobenzonitrile(cas: 1194-02-1) is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.Category: nitriles-buliding-blocks
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts