In 2022,Wang, Shuai; Li, Xin; Jin, Shengnan; Liu, Kang; Dong, Cong; Su, Jianke; Song, Qiuling published an article in Organic Chemistry Frontiers. The title of the article was 《Difluorocarbene-enabled access to 1,3-oxazin-6-ones from enamides》.Recommanded Product: 4-Fluorobenzonitrile The author mentioned the following in the article:
An efficient and general strategy for the construction of 1,3-oxazin-6-ones with high efficiency and chemoselectivity was reported. Instead of using CO as a C1 source, difluorocarbene was introduced as a carbonyl provider. This method featured readily available starting materials and valuable products, good functional group tolerance and simple operation. In the part of experimental materials, we found many familiar compounds, such as 4-Fluorobenzonitrile(cas: 1194-02-1Recommanded Product: 4-Fluorobenzonitrile)
4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.Recommanded Product: 4-Fluorobenzonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts