《High-Contrast Polymorphic Luminogen Formed through Effect of Tiny Differences in Intermolecular Interactions on the Intramolecular Charge Transfer Process》 was published in Advanced Optical Materials in 2020. These research results belong to Wang, Kang; Xie, Yujun; Liu, Ming; Tao, Wei; Zhang, Hao; Huang, Meidong; You, Jinmao; Liu, Ying; Li, Yunliang; Li, Zhen; Dong, Yong Qiang. Category: nitriles-buliding-blocks The article mentions the following:
Polymorphic luminogens provide the opportunity to disclose relation between the packing patterns and performance of luminogen and facilitate design of high performance luminogens. However, the effect of intramol. charge transfer (ICT) is seldom used to construct luminogens with polymorphs, though the ICT process is very sensitive to microenvironment. In this work, 2-(3-(diphenylamino)-9H-xanthen-9-ylidene)-malononitrile (DPAXM, 1) with donor-acceptor structure exhibits high contrast polymorphism dependent emission due to the effect of tiny differences of intermol. interactions on ICT process. Three crystals of 1 with nearly identical structures emit yellow, orange, and red light with sequentially decreased efficiency which is attributed to ICT process modulated by the tiny differences in intermol. interactions. In addition to ground state study, excited state of the polymorphs is investigated by time-resolved ultrafast transient mid-IR spectroscopy and theor. calculation Nonemissive crystals of 1 can also be obtained. The modulation of ICT effect by intermol. interactions may provide a reference for the mol. design of high-performance luminogens. The results came from multiple reactions, including the reaction of 4-Bromo-2-fluorobenzonitrile(cas: 105942-08-3Category: nitriles-buliding-blocks)
4-Bromo-2-fluorobenzonitrile(cas:105942-08-3) is used as a reagent in the synthesis of picolinamide derivatives as a novel class of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors.Category: nitriles-buliding-blocks 4-Bromo-2-fluorobenzonitrile is also used in the preparation of fluorinated CB2 receptor agonists for PET imaging.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts