In 2017,Sonyanaik, Banoth; Sakram, Boda published 《Design and synthesis of novel substituted 1,8-naphthyridin-2-yl-amide derivatives at ambient temperature and evaluation of their antimicrobial activity》.Heterocyclic Letters published the findings.Application In Synthesis of 2-(3-Bromophenyl)acetonitrile The information in the text is summarized as follows:
A new series of substituted 1,8-naphthyridin-2-yl-amide derivatives I (R1 = H, 3-NO2, 4-Br, etc.; R2 = H, 4-Cl) have been successfully synthesized in good yields at ambient temperature by reaction of various substituted 3-phenyl-1,8-naphthyridin-2-amines with aryl benzoic acids. All the newly synthesized compounds were evaluated for their in vitro antimicrobial activity. All these compounds exhibit good antibacterial and excellent antifungal activity. Among them, compound I (R1 = H, 4-Br, 4-NO2; R2 = 4-Cl) showed remarkable inhibition of antimicrobial activity. The results came from multiple reactions, including the reaction of 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Application In Synthesis of 2-(3-Bromophenyl)acetonitrile)
2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) has been used in the synthesis of 2-(1-cyano-1-(3-bromophenyl))methylidene-3-phenylthiazolidine-4,5-dione or a series of aminoethylbiphenyls, novel 5-HT7 receptor ligands.Application In Synthesis of 2-(3-Bromophenyl)acetonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts