The author of 《Bis-salophen palladium complex immobilized on Fe3O4@SiO2 nanoparticles as a highly active and durable phosphine-free catalyst for Heck and copper-free Sonogashira coupling reactions》 were Sardarian, Ali Reza; Kazemnejadi, Milad; Esmaeilpour, Mohsen. And the article was published in Dalton Transactions in 2019. Related Products of 623-00-7 The author mentioned the following in the article:
New Fe3O4@SiO2 core-shell superparamagnetic nanoparticles functionalized by a bis-salophen Schiff base Pd complex were synthesized and employed as an efficient magnetic nanocatalyst in the Heck and Sonogashira cross coupling reactions. The synthesized nanostructures were characterized by FTIR spectroscopy (FTIR), XRD, dynamic light scattering (DLS), energy dispersive X-ray anal. (EDX), XPS, elemental anal. (CHN), cyclic voltammetry (CV), Brunauer-Emmett-Teller anal. (BET), and UV-visible spectroscopy. The morphol. and size of the nanoparticles were studied by FE-SEM and TEM analyses. The magnetic properties of the catalyst were studied by VSM anal. The loading content and leaching amounts of Pd on the catalyst were measured by inductively coupled plasma (ICP) anal. The thermal behavior of this magnetic heterogeneous catalyst was studied using a TGA instrument. This heterogeneous catalytic system showed a good performance in the coupling of aryl halides with alkynes (Sonogashira reaction) as well as aryl halides with alkene derivatives (Heck reaction). High to excellent yields were achieved for these C-C coupling reactions. The catalyst can be simply separated from the reaction media by an external magnet and reused for 8 consecutive runs without any significant loss of activity. The kinetics of the reactions were studied. After reading the article, we found that the author used 4-Bromobenzonitrile(cas: 623-00-7Related Products of 623-00-7)
4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.Related Products of 623-00-7 It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts