In 2018,Soft Matter included an article by Pocock, Emily E.; Mandle, Richard J.; Goodby, John W.. Name: 4-Bromo-2-fluorobenzonitrile. The article was titled 《Molecular shape as a means to control the incidence of the nanostructured twist bend phase》. The information in the text is summarized as follows:
Eleven novel materials I [R = 4-(4-CNC6H4)C6H4, 4-(3,4-di-FC6H4)C6H4, 4-(4-F5SC6H4)C6H4, etc.] with all found to exhibited the twist-bend phase and a linear relationship between TN-I and TTB-N were prepared and studied. A computational study of the conformational landscape revealed the octamethyleneoxy spacer to had a broader distribution of bend-angles than the nonamethylene equivalent, leading to reductions in the thermal stability of the TB phase. This result indicates that a tight distribution of bend-angles should stabilize the TB phase and lead to direct TB-Iso phase transitions, and conversely a broader distribution should destabilize the TB phase which may allowed new states of matter that were occluded by the incidence of this phase to be revealed. In the part of experimental materials, we found many familiar compounds, such as 4-Bromo-2-fluorobenzonitrile(cas: 105942-08-3Name: 4-Bromo-2-fluorobenzonitrile)
4-Bromo-2-fluorobenzonitrile(cas:105942-08-3) is used as a OLED intermediate, Pharmaceutical, electronic and chemical intermediate.Name: 4-Bromo-2-fluorobenzonitrile It is used in the synthesis of heterocycles and liquid crystals.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts