SDS of cas: 614-16-4In 2019 ,《Chemo- and Diastereoselective Synthesis of Pyrazolo-tetrahydropyridines via Multicomponent Sequential Aza-Diels-Alder Reactions in Water》 appeared in ChemistrySelect. The author of the article were Nazeri, Mohammad Taghi; Javanbakht, Siamak; Shaabani, Ahmad; Khavasi, Hamid Reza. The article conveys some information:
A novel and an efficient strategy for the synthesis of chemo- and diastereoselective synthesis of pyrazolo-tetrahydropyridines I [X = O, NMe; Y = C, SO; R1 = Me, Ph; R2 = H, Br, OMe, naphthyl; Ar = Ph, 4-ClC6H4] via a one-pot multi-component intramol. aza-Diels-Alder reactions (ADARs) from benzoylacetonitrile derivatives, phenylhydrazine, salicylaldehyde derivatives, and styrenesulfonyl or cinnamoyl chloride in H2O as a green solvent was reported. This synthesis procedure was also designed to follow the group-assisted purification (GAP) chem., which could avoid traditional purification such as recrystallization and chromatog. methods.3-Oxo-3-phenylpropanenitrile(cas: 614-16-4SDS of cas: 614-16-4) was used in this study.
3-Oxo-3-phenylpropanenitrile(cas: 614-16-4) has been used in the synthesis of substituted naphtho[1,8-bc]pyrans. It was also used as building block in the preparation of 4H-pyrans, 2-pyridones, furans and carbocyclics.SDS of cas: 614-16-4
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts