In 2019,Nature Communications included an article by Nambo, Masakazu; Yim, Jacky C.-H.; Freitas, Luiza B. O.; Tahara, Yasuyo; Ariki, Zachary T.; Maekawa, Yuuki; Yokogawa, Daisuke; Crudden, Cathleen M.. Related Products of 17201-43-3. The article was titled 《Modular synthesis of α-fluorinated arylmethanes via desulfonylative cross-coupling》. The information in the text is summarized as follows:
Herein, Pd-catalyzed Suzuki-Miyaura cross-coupling of α-fluorinated benzylic triflones with arylboronic acids affording structurally diverse α-fluorinated diarylmethanes Ar1C(X)(F)Ar2 [Ar1 = 4-t-BuC6H4, 4-O2NC6H4, 4-CO2MeC6H4, etc.; Ar2 = Ph, 2-MeC6H4, 1-naphthyl, etc.] was reported. The ease of synthesis of fluorinated triflones as the key starting materials enabled powerful late-stage transformations of known biol. active compounds into fluorinated analogs. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanobenzyl bromide(cas: 17201-43-3Related Products of 17201-43-3)
4-Cyanobenzyl bromide(cas: 17201-43-3) is used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile. It is also useful in the preparation of 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile by reaction with 2H-tetrazole in the presence of potassium hydroxide.Related Products of 17201-43-3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts